Advanced analytical and characterization techniques

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Rheological studies on fluid and semifluid systems
Keywords
Analysis DSC
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Recording Circular Dichroism spectra (UV-vis;NIR-IR)
Keywords
Circular dichroism, Absolute configuration
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Aminoacidemic profile
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Metabolism, Clinical chemistry, Chemokines, Cytokines
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Metabolomics characterization by NMR of tissues, biological and agro-food samples
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NMR, Metabolomics, Analysis of biological samples
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Characterization of molecules and protein, study of the ligand-receptor interaction by NMR spectroscopy (up to 950 MHz)
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NMR
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UV-Vis and Raman measurements to determine micro pollutants and molecule-substrate interaction.
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Chemical Sensors
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Absolute configuration determination
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NMR
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Chemokines, cytokines, apolipoprotein determination
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Metabolism, Clinical chemistry, Chemokines, Cytokines
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Trace metal content analysis
Keywords
Analysis of metals
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Sample analysis by mean of NMR spectrometer (1H, 13C, 2D)
Keywords
NMR
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Protein/polypeptides secondary strucutre determination
Keywords
NMR
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Search and dosage of narcotics, drugs and their metabolites on biological samples (blood, urine, saliva, hairs)
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GC/MS
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Single crystal X-ray data collection and structure resolution. Powder diffraction X-ray data collection and qualitative/semiquantitative analyses. High resolution X-ray microtomography image collection and analysis. Elemental analysis through wavelength d
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Micro- CT
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Analysis of folding and aggregation state of proteins (with particular reference to the neurological field) by dynamic light scattering, circular dichroism, IR, fluorescence
Keywords
Circular dichroism, Neurodegeneration
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Analysis and characterization of small molecules and polymeric materials by NMR
Keywords
NMR
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Analysis and consultancy of perceptive, cognitive, emotional capabilities in man based on neurobiological and psycological data, for forensic and marketing applications
Keywords
Decision-making, Cognitive ability, Perceptual skills
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Analysis by mass spectrometry (several MS techniques available)
Keywords
GC/MS, TOF/TOF, MALDI/TOF
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Enzymatic activity determination by HPLC analysis
Keywords
Enzyme activity
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Enantiomeric purities and absolute configurations of chiral drugs by NMR
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NMR
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Gamma-glutamiltransferase isoforms determination by HPLC
Keywords
Gamma -glutamyltransferase, Cardiac risk, Alcohol Abuse
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Chemical and physical analysis on water, soil, vegetable and foods
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Determination fo purinic, pyrimidinic, pyridinic compounds in biological samples
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Analysis of purines, Analysis of pyrimidine
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Stability of pharmaceutics by NMR kinetics determinations
Keywords
NMR
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S-nitrosglutathione and nitrosothiols determination
Keywords
Gamma -glutamyltransferase, Cardiac risk, Alcohol Abuse
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Analysis of small molecules and biomolecules by mass spectometry (TSQ HPLC/ Maldi TOF/ LTQ Orbitrap)
Keywords
MALDI/TOF
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Proteomic, redoxomic, immunoproteomic analysis by bidimensional electrophoresis
Keywords
Proteomics, Peptidomica, Redoxomica
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Water determination in biomaterials by NMR
Keywords
NMR
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Drug purity determination by GC/MS and LC/MS
Keywords
GC/MS
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Analysis and characterization by NMR
Keywords
NMR
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Peptidomic analysis by SELDI ToF/MS
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SELDI -TOF
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DSC analysis
Keywords
Analysis DSC, Pharmaceutical formulation
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Enantiopurity determination and semi-preparative separation of racemic mixtures
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GC/MS
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Characterization of systems by UV/Vis spectroscopy
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Spectroscopy UV/Vis
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NMR analysis for interactions study between para- and diamagnetic metals and peptides or proteins
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NMR
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Determination of the osmolality of solutions
Keywords
Osmolality
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SEM, TEM, AFM, Raman, confocal microscopy for characterization at high-spatial resolution (nanometer scale)
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SEM, MET, Raman
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Structural characterization of micro and nanosystems (Analysis SAXS, WAXD, GISAXS, zeta potential, fluorescence, CD);Morphology and structural properties of biofilms and biomolecules at the solid/liquid
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Nanoparticles, X-ray Diffraction
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EPR analysis to characterize systems containing paramagnetic metals (enzymes, radical species, complexes), reactive oxygen species, lipid-protein interactions, nanomaterials
Keywords
EPR
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Determination of the reological behaviour of liquid and semisolid materials performed with rotational viscosimeter (HAAKE RheoStress 1)
Keywords
Rheological properties
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Development of chromatographic methods for quali and quantitative analysis by HPCL-DAD, HPLC-MS/MS of drugs, cosmetics, food supplements, herbal products
Keywords
Chromatographic methods, Purity drugs
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Structural analysis by electronic microscopy (CryoTEM also available) of biomaterials, tissues, cell systems
Keywords
CryoTEM
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Quali and quantitative analysis of active ingredients and drugs, health products (integrators, nutraceuticals), medical aids
Keywords
Nutritional Supplements, Analysis of Drugs, Quality control
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Targeted metabolomics by MS
Keywords
HPLC/MS, Metabolomics, Newborn screening, Rare diseases
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Isolation and structural characterisation of secondary constituents of plants by HPLC-DAD, HPLC-MS
Keywords
Purity drugs
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GC-MS analysis and characterization of organic compounds
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GC/MS
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Application and development of certified methods for quality control, extraction procedures from different matrices, analysis of metabolites and impurities, kinetic and nutraceutical studies
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Nutritional Supplements, Analysis of Drugs, Quality control
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Development of new test for metabolites and drugs measurements
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Biomarkers, Drug dosage, Chromatographic methods
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Characterization of magneto-optical and structural properties of nanostructured samples
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EPR
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Chiral stationary phase HPLC and GC analyses for the enantiomeric purity determination of organic compounds
Keywords
Enantiomeric excess
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Solid state NMR analysis
Keywords
Liquid Crystals, Molecular dynamics
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Specific Absorption Rate (SAR) evaluation at freqeuzcies of few hundreds of kHz
Keywords
Specific absorption rate
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Kinetic studies. Stability check against ageing
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Fluorescence Analysis, Molecular interactions
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Separation of natural compounds and their characterization
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Extracting natural compounds, Essential Oils
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DSC analysis for determination of thermal curves, purity, crystallinity degree, polymorphism, thermal stability, compatibility studies,characterization of binary systems and interaction products
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Analysis DSC
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Determination of pollutants by optical spectroscopy
Keywords
Fluorescence Analysis, Molecular interactions
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Quality control of plant extract
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Extracting natural compounds, Essential Oils
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Mean size, polydispersity index, Zeta-potential determination
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Analysis DSC
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Determination of the binding constant between biomolecules and small molecules
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Fluorescence Analysis, Molecular interactions
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Clinical chemistry analytes determination
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Metabolism, Clinical chemistry, Chemokines, Cytokines
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Microbial analysis

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Environmental microbiology analyses
Keywords
Microbial Indicators, Deletion mutants, Endophytes
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Bacterial genomics
Keywords
Microbial Indicators, Deletion mutants, Endophytes
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Microbiological analysis water
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Analysis biohazard, Environmental security, Food Safety
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Virological analysis of marine sediments
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Analysis biohazard, Environmental security, Food Safety
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Analysis of viruses in food and environmental matrices
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Analysis biohazard, Environmental security, Food Safety
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Probiotics strain characterization for human use
Keywords
Recombinant probiotic strains, Microbial Infections, Antimicrobial
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Microarray analysis for mycetes molecular diagnosis
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Recombinant probiotic strains, Microbial Infections, Antimicrobial
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Bioengineering

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Development and characterization (auditory tests) of prosthesis and reconstruction techniques for ear surgery
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Test sound, Biomaterials, Bones Earrings, Prosthetic Ear

Drug discovery and design

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Synthesis of derivatives on demand
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Synthesis glycopeptides, Mimetic sugar
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Synthesis (limited amounts) of heterocyclic compounds
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Custom synthesis
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Design and synthesis of new drugs, in particular aspartic proteases inhibitors, integrin ligands, peptidomimetics, strigolactone analogues, adenine conjugates
Keywords
Drug Design
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Custom synthesis of bioactive molecules and their characterization
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Custom synthesis, Drug Design, Drug delivery
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Purification and characterization of oligosaccharides from complex matrix
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Synthesis glycopeptides, Mimetic sugar
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Educational training in biomedical field

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Surgical Training using advanced simulators
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Surgical Education
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Multimedia training in health
Keywords
Webinar, Web -based learning
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Simulation in the field of endoscopy
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Webinar, Web -based learning

Informatics for life sciences

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Consultancy activities on ICT topics
Keywords
Sensors, Wireless, Telemedicine
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Software architetcures and Information systems for the healthcare system and diagnostic devices
Keywords
Software for Health, Software for medical devices, Image Processing
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Image and video processing, multimedia digital libraries
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Software for Health, Software for medical devices, Image Processing
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Development of software and computer applications for search, retrieval, analysis and use of information contained in large collection of data (Web search, Information Retrieval, Data Mining, XML processing e indexing, Natural Language Processing)
Keywords
Data Mining, Information retrieval, Big data handling
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Nuclear medicine - synthesis of radioactive substances and diagnostic applications

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Synthesis of radiolabelled compounds for molecular imaging
Keywords
Micro- PET and PET/SPECT/CT, Molecular Imaging, Radiochemistry
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PET/SPECT/CT and microPET/SPtrCT/CT analysis
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Micro- PET and PET/SPECT/CT, Molecular Imaging, Radiochemistry
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Development of radiolabelled probes for molecular imaging
Keywords
Radioactive Probes
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Animal models

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Production of genetically modified mice
Keywords
Preclinical Animal Models, Animal models of xenograft
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Mouse models of obesity and insulin resistance for metabolic studies related to type 2 diabetes and metabolic syndrome
Keywords
Diabetes Mouse Model
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Animal models of lung emphysema for the study of chronic obstructive pulmonary disease (COPD)
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Murine Model COPD
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Animal models of Lung Hypertension
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Pulmonary Hypertension, Pulmonary Fibrosis, Murine models, Preclinical
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Animal models of Lung Fibrosis (IPF, NSIP e SIRLD)
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Pulmonary Hypertension, Pulmonary Fibrosis, Murine models, Preclinical
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Animal modles of Emphysema and COPD
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COPD, Emphysema, Murine models
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In vivo microimaging fro studies on animal models by high resolution ultrasound system
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Microimaging ultrasound in vivo

2D and 3D Scaffold

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Rapid Prototyping of personalized organ models based on bioimaging data
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Rapid Prototyping

Protein/peptide synthesis and characterization

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Production of monoclonal antibodies and their genetically modified derivatives
Keywords
Production of antibodies
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Synthesis of peptides and peptide libraries.
Keywords
Synthesis branched peptides
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Synthesis and characterization of recombinant proteins
Keywords
Synthesis recombinant proteins, Characterization of protein
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Expression purification, refolding and functional analysis of recombinant proteins
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Synthesis recombinant proteins, Characterization of protein, Growth Factors
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Characterization of antigen-antibody interactions using an optical biosensor
Keywords
Biomarkers

Diagnosis technologies

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Development of single cell and tissue manipulation and diagnostic by optical and magnetic spectroscopy
Keywords
Biophotonics, Medical imaging, Microscopy
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Objective analysis of audio signals of clinical interest. Applications: dysphonic subjects, newborn infant cry, singing voice
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Non-invasive diagnostics, Analysis of vocal emissions, Autism, Analysis of biomedical signals, Image Analysis
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Development of custom biomedical ultrasound diagnostic systems
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Doppler
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Ultrasonic and laser tissue characterization
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Laser
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Evaluation of the interaction of optic and electromagnetic radiation with biological tissues and cells for diagnostic and therapeutic purposes
Keywords
Laser
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Determination of quantitative neurological markers by MRI
Keywords
Indexes neurological, MRI
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Tuberculosis diagnostic assays. Molecular typing (spoligotyping, VNTR-MIRU) of clinical isolates of Mycobacterium tuberculosis
Keywords
Tuberculosis, Diagnostic tests
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Single fiber (SFEMG) and quantitative electromyography for the study of neuromuscular system
Keywords
Neurophysiology, Motor system, Evoked Potentials
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Evoked potentials stimulus and related event
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Neurophysiology, Motor system, Evoked Potentials
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Clinic immunoparasitology: evaluation of new diagnostic assays of most interesting parasitic diseases
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Immunoparassitologia clinic, Nematodes

Genetic analysis

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Genetic diagnosis for tumors
Keywords
Tumor Metabolism, Genetic analysis
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Automated extraction of nucleic acids and their quantitative and qualitative determination
Keywords
PCR, Differential gene expression, Polymorphisms, Statistical Analysis
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Molecular biological analysis on tumor cells and circulating free DNA
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Biomarkers
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Primer design for RT-qPCR, HRM-PCR and Sanger sequencing. qPCR experiments
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PCR, Differential gene expression, Polymorphisms, Statistical Analysis
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Analysis and sequencing of DNA and microRNA
Keywords
Biomarkers
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Bioinformatics support to gene expression experiments (microarray and qPCR)
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PCR, Differential gene expression, Polymorphisms, Statistical Analysis
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Evaluation of the protective action of natural compounds, drugs and foodstuffs on colorectal carcinogenesis
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Analysis of DNA and RNA, RT - qPCR, Polymorphisms, HPLC
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Genetic mutation analysis by DHPLC
Keywords
DHPLC
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Genotyping (polymorphism analysis)
Keywords
Genotyping, Polymorphisms
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Quantitative analysis by qPCR and MLPA
Keywords
Genetic analysis, PCR, NGS Sequencing
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mRNA quantification
Keywords
Quantification of mRNA
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Traditional automatic sequencing and next generation sequencing (NGS)
Keywords
Genetic analysis, PCR, NGS Sequencing
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Qualitative and quantitative PCR. DNA sequencing. Polymorfisms in hematological diseases
Keywords
PCR
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CGH array analysis
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Genetic analysis, PCR, NGS Sequencing
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Cytogenetic analyses. Analysis of gene polymorphisms
Keywords
Polymorphisms, Nanotoxicity, Epigenetics
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Estimation of the genetic variability of populations
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Population Genetics, Phylogenetic
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Genotoxicity and cytotoxicity studies in cell cultures treated with nanomaterials (nanotubes, metal oxide nanoparticles)
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Polymorphisms, Nanotoxicity, Epigenetics
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Geographic/ethnic/genealogical ancestry assignment by DNA analyses
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Population Genetics, Phylogenetic
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Genetic analyses on degraded DNA for personal identifications (DNA fingerprinting)
Keywords
DNA analysis, Counterfeit
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DNA sequence analysis and DNA fragment sizing
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Analysis of genetic diversity, DNA analysis
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Genetic heterogeneity of HBV, HCV and HDV genomes
Keywords
Genotype HBV , HCV, HDV
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Quantification of DNA, cDNA or RNA targets
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Analysis of genetic diversity, DNA analysis
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Genetic profiling of IL28B gene for sensitivity to IFN therapy and JAK2 V617F gene
Keywords
Genotype HBV , HCV, HDV
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Identification of specific animal and plant components in food
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DNA analysis, Tests of genetic assignment
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Genetic heterogeneity of HBV and HCV genes for antiviral resistance
Keywords
Genotype HBV , HCV, HDV
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Interleukin 28B (Interferon-Lambda3) genotyping
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Polymorphisms
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Quantification of markers of mmajor heoatitis viruses: HBV-DNA, HCV-RNA, HDV-RNA, HBsAg and IgM antibodies
Keywords
Genotype HBV , HCV, HDV
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Analysis of the effects of new therapies against viral hepatitis and related disorder
Keywords
Therapy hepatitis
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Genetic screening for dyslipidemia
Keywords
Genetics of Diabetes, Genetics of dyslipidemia
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Molecular diagnosis of neurological diseases (dementias, hereditary ataxias, amyotrophic lateral sclerosis, Huntington's disease)
Keywords
Biomarkers
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Monogenic diabetes screening
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Genetics of Diabetes, Genetics of dyslipidemia
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Cerebrospinal liquoral biomarkers for neurodegenerative diseases
Keywords
Biomarkers
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Genotyping
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PCR, Differential gene expression, Polymorphisms, Statistical Analysis

Biological/biochemical analysis and assays

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Biological samples analysis by TEM and SEM microscopy
Keywords
MET, SEM
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Evaluation of enzymatic activities of oxidative cellular metabolism for the diagnosis of neurological diseases
Keywords
Biomarkers, SLA, Alzheimer's
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Functional test for adhesion, cell migration and invasion, cell proliferation and survival, DNA synthesis, apoptosis and senescence
Keywords
Adhesion Test, Pharmacological Screening
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Plant samples and extracts analysis by light and electronic microscopy
Keywords
MET, SEM
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Quantification of neurodegenerative protein biomarkers in biological matrices
Keywords
Biomarkers, SLA, Alzheimer's
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In vitro angiogenesis tests
Keywords
Adhesion Test, Test of angiogenesis, Pharmacological Screening
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Kinetic and thermodynamic analysis of biomolecular interaction by Biacore
Keywords
Biacore
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Optical spectroscopy and electropotentiometric methods applied to determine drug interactions in cells in the cardiovascular field
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Cardiovascular Pharmacology, Nitric Oxide, Hydrogen sulfide, Anti hypertensive, Anti ischemic
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Development of analytical assays to quantitatively evaluate biomolecules
Keywords
Enzyme Kinetics
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Screening of peptides for drug discovery
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Biacore
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Nitric oxide and hydrogen sulfide determination in cell systems
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Cardiovascular Pharmacology, Nitric Oxide, Hydrogen sulfide, Anti hypertensive, Anti ischemic
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Development of methods to determine autoantibodies (using autoantigens, synthetic peptides)
Keywords
Immunology, Autoantigens, Synthetic peptides
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Quality control of production batches of biotech drugs
Keywords
Quality control, Biotech drugs
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Morpho-functional analysis of kidneys. Glomerular filtrate determination
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Diagnosis of renal damage
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Immunoenzymatic techniques (evaluation of hormones, steroids, growth factors, chemokines, cytokines)
Keywords
Dosage hormones, Dosage neurotrophic factors, Techniques immunoassays
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High throughput technologies for large scale autoantibody screening in diabetes mellitus and in coeliac disease
Keywords
Dosage autoantibodies, Diabetes, Celiac Disease
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Cytofluorimetry & cell sorting
Keywords
Cell sorting
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Cell parameters analyses (cell cylce, mitochondrial membrane potential, senescence, apoptosis parameters, neuronal sprouting, tumoral cell migration, angiogenesis, enzyme activity,zymography)
Keywords
Dosage hormones, Dosage neurotrophic factors, Techniques immunoassays
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Analysis by laser capture microdissection microscopy
Keywords
Laser microdissection
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Confocal microscopy and laser dissection analysis
Keywords
Cell sorting
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Culture model for drug permeability testing
Keywords
Epithelial Permeability, Respiratory disorders, Pharmacokinetics
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FISH and electronic microscopy
Keywords
FISH
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Analysis of oxidative stress, motility, adesion, metabolism in cells. Intra and intercellular molecular pathways, in particular related to tumors
Keywords
Cell Motility, Tumor Metabolism, Oxidative stress, Cell Signaling
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In vitro study of cigarette smoke-induced epithelial barrier dysfunction
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Epithelial Permeability, Respiratory disorders, Pharmacokinetics
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Time lapse analysis by CO2 microscope
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Isolation and analysis of circulating tumor cells in biological samples by ISET
Keywords
Circulating tumor cells
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Functional analysis of immune cells (phosphorylative pattern analysis, intracellular calcium fluxes, cytokines production, chemotaxis, , apoptosis)
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Functional analysis of cells
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Biological samples analysis for diagnostic routine in medical assistance
Keywords
Circulating tumor cells
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Aminoacid analysis fo biological fluids by microHPLC
Keywords
Biomarkers
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Hormone dosage for analysis in endocrinology
Keywords
Circulating tumor cells
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Metal analysis by ICP OES
Keywords
ICP OES
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Service in development for 2D-gel quantification and statistical analysis of protein spots
Keywords
Proteomics, Analysis of 2D gel, Protein Expression
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Neurotrophic factors assay hormones : BDNF, oxytocin, ATP
Keywords
Neurotrophic factors
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Sample analysis by SDS-PAGE and western blot
Keywords
Proteomics, Analysis of 2D gel, Protein Expression
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Pancreatic hormone assay
Keywords
Pancreatic Hormones, Diabetes Antibodies
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Protein/peptide sample characterization by LC-MS
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Proteomics, Analysis of 2D gel, Protein Expression
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Diabetes-related autoantibodies
Keywords
Pancreatic Hormones, Diabetes Antibodies
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Real time PCR and cytofluorimetry, with particular reference to the immunological field
Keywords
PCR
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Chemical-physical and biochemical analysis of cerebrospinal fluid in neurological diseases, inflammatory, degenerative and autoimmune
Keywords
Biomarkers, SLA, Alzheimer's
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Toxicological tests and pharmacological screening on human and animal cells
Keywords
Toxicological tests, Pharmacological Screening
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Molecular biology/biochemistry

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Supply of microsomes containing CaATPase;supply of membrane fragments containing Na,KATPase
Keywords
Biomimetic membranes, Interaction drug/ion channels, Interaction Drugs/ATPase, Electrochemistry
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Spectrophotometric determination of ATPase hydrolytic activity of ion pumps
Keywords
Biomimetic membranes, Interaction drug/ion channels, Interaction Drugs/ATPase, Electrochemistry
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Safety cardiac test on hERG channel expressed in HEK293 cells or in Xenopus laevis oocytes by patch-clamp
Keywords
Biomimetic membranes, Interaction drug/ion channels, Interaction Drugs/ATPase, Electrochemistry
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Evaluation of biological effects of drugs and nutraceuticals on skeletal muscle, liver epithelial, neuroblastoma cells
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Biomarkers
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Use of recombinant antibodies for detecting biomolecules and enviromental toxic products
Keywords
Biomarkers
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Preparation and characterization of beta cell line and human pancreatic islets
Keywords
Diabetes, Beta cell function, Islet transplantation
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Drug screening

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In vitro chemosensitivity, cytotoxicity, angiogenesis inhibition tests
Keywords
Cytotoxicity, Angiogenesis inhibitors, Pharmacogenetics oncology
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Identification and characterization of new compounds or natural extracts able to relieve pain and induce neuroprotection
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Analgesia
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Development of carbonic anhydrase inhibitors and related activity tests
Keywords
Metalloproteins, Carbonic anhydrase, Hypoxic tumors
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Characterization of the enzymatic kinetics of matrix metalloproteases inhibitors
Keywords
Enzyme Kinetics, Angiogenesis inhibitors
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Known organic active compounds preparation and development of synthetic methods for the preparation of new drugs
Keywords
Drug screening
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Development of scale up preparation of known active ingredients
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Drug screening
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Screening of compound libraries
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Drug Design
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Drug delivery & Formulation

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Synthesis and characterization of magnetoliposomes for drug and gene delivery
Keywords
Drug delivery
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Thermodynamics, stability, molecular recognition and application of biomacromolecules and drugs
Keywords
Thermodynamic Properties, Molecular interactions
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Synthesis and functionalization of nanoparticles for drug delivery
Keywords
Drug delivery
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Optimisation of stability and biopharmaceutical and technological characteristics of herbal drugs, their preparations and herbal medicinal products
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Stability Test, Liposomes, Michelle
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Development of modified, targeted or controlled-release dosage forms of drugs
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Solubility Drugs, Controlled release, Releasing the site - specific
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Improvement of solubility and bioavailability of poorly water soluble drugs
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Solubility Drugs, Controlled release, Releasing the site - specific
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Corrosivity test (OECD 431/2004)
Keywords
Pharmaceutical Technology, Controlled release, Pharmaceutical formulation, Stability Test
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Irritation test (OECD/OCDE 439/2010)
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Pharmaceutical Technology, Controlled release, Pharmaceutical formulation, Stability Test
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Disintegration test of tablet and suppository
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Pharmaceutical Technology, Controlled release, Pharmaceutical formulation, Stability Test
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Dissolution test of tablets, capsules, and transdermal patches
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Pharmaceutical Technology, Controlled release, Pharmaceutical formulation, Stability Test
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Evaluation of muco-adhesive properties of liquid and semisolid formulations
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Pharmaceutical Technology, Controlled release, Pharmaceutical formulation, Stability Test
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Freeze-drying and spray-drying of aqueous samples
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Pharmaceutical Technology, Controlled release, Pharmaceutical formulation, Stability Test
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Giant Unilamellar Vesicles: prepraration and characterization at the Confocal Microscope
Keywords
Drug delivery
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Formulation and preparation of monodisperse liposomes (diameters 200-20 nm), micelles, microemulsions with inclusion of active ingredients
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Drug delivery
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Biocompatible materials

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In vitro biocompatibility, bioactivity, toxicity and genotoxicity evaluation of drugs and biomaterials
Keywords
Biocompatible, Biodegradable, Tissue engineering, Theranostics, Biomaterials
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Synthesis and chemical-physical characterization of biomaterials
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Biocompatible, Biodegradable, Tissue engineering, Theranostics, Biomaterials
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Material and biological tissue characterization
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Gait analysis
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Analysis of mechanical properties of biological tissue in vivo and in vitro
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Gait analysis
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Biodegradation Tests
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Biocompatible, Biodegradable, Tissue engineering, Theranostics, Biomaterials

Drug metabolism and PK

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Dissolution test, in vitro gastric absorption and release of solid or semisolid drugs/active ingredients
Keywords
Drug delivery
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Dissolution rate studies of conventional or non conventional dosage forms of drugs
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Drug delivery
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Drug permeation studies in vitro (through synthetic menbrans) or ex vivo (through excissed human or animal skin)
Keywords
Drug delivery
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In vitro and in vivo pharmacodynamicand toxicity analysis of pharmaceutical compounds, mainly oncological compounds
Keywords
Pharmacodynamics, Cell Therapy
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Analysis of clonogenicity and in vivo carcinogenicity of cellular samples (mainly stem cells) to be applied for therapeutic purposes
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Pharmacodynamics, Cell Therapy
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Therapeutic drug monitoring (PK-PD) of antifungal and antimicrobial drugs by HPLC assay
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Antimicrobial Chemotherapy, Evaluation of the PK -PD
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Therapeutic Drug Monitoring and pharmacokinetics profile in biological fluids and dried blood spot
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Pharmacodynamics, Pharmacokinetics, Drug dosage
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Pharmacokinetic model of population, therapeutic monitoring, pharmacokinetic of chemiotherapeutics
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Pharmacogenetics, Pharmacokinetics, Anticancer, Preclinical
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In vitro and in vivo preclinical trials using antiangiogenetic drugs against tumor pathologies angiogenesis-related
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Pharmacogenetics, Pharmacokinetics, Anticancer, Preclinical
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Nanotechnology

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Synthesis, functionalization (antibodies, DNA, SiRNA, aptamers, peptides and proteins) and characterization of nanomaterials for imaging, drug delivery, hyperthermia and photothermia.
Keywords
Nanocarriers
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Drug safety

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Assessment of efficacy and safety, also in the field of integrative medicine (herbal medicine, acupuncture and traditional Chinese medicine)
Keywords
Pharmacovigilance, Phytovigilance, Integrative medicine
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Analisis, evaluation and realization of information technology databases for pharmacology and pharmacovigilance
Keywords
Pharmacovigilance, Phytovigilance, Integrative medicine
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Pre-clinical trials

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Preclinical studies on acute and chronic pain mechanisms
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Analgesia
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Biobanking

Service details
Storage and distribution of biological samples and associated data for research
Keywords
Biobanks, Human samples and associated clinic/biological data, Samples traceability
Service details
Support about management, procedures and regulatory aspects of biobanks
Keywords
Biobanks management, Biobanks standard operating procedures
Service details
Extraction, treatment and characterization of biological samples and sub-molecules
Keywords
Biological samples extraction, Biological samples characterization